The absence of evidence is not the evidence of absence
نویسندگان
چکیده
منابع مشابه
Absence of evidence is not evidence of absence.
Randomized controlled clinical trials are conducted to determine whether differences of clinical importance exist between selected treatment regimens. When statistical analysis of the study data finds a P value greater than 5%, it is convention to deem the assessed difference nonsignificant. Just because convention dictates that such study findings be termed nonsignificant, or negative, howev...
متن کاملMolecular carriers of acquired inheritance: absence of evidence is not evidence of absence
In utero exposure to environmental endocrine disruptors can cause transgenerational effects in the males of subsequent generations. DNA methylation (5 mC) was suggested, but being challenged as the molecular carrier of such epigenetic information. In a recent study, Schuster et al. show a changed small RNA profile changed in the sperm of F3 generation after F0 in utero vinclozolin exposure, sug...
متن کاملFluoridation of drinking water and chronic kidney disease: absence of evidence is not evidence of absence.
Sir, Ludlow et al. [1] only confirmed that our knowledge of the potential adverse effects of chronic low fluoride supplementation of drinking water on normal or diseased kidneys is insufficient. More than 60 years after water fluoridation, there is no high-level evidence as most published studies are small, have methological deficiencies or are otherwise flawed. There are two areas of concern r...
متن کاملSupplemental oxygen and dypsnoea in interstitial lung disease: absence of evidence is not evidence of absence.
It is with great interest that we read the recent systematic review by BELL et al. [1] concerning the effects of oxygen therapy on dyspnoea and exercise capacity in patients with interstitial lung disease (ILD). The authors report that, while supplemental oxygen increases exercise capacity, it does not improve dyspnoea. Overall, this is a well-executed systematic review that accurately reflects...
متن کاملIn “Cryptic” Population Dynamics, Absence of Evidence Is Not Evidence of Absence
1838 When the populations of two species oscillate together, it's a good bet that they are tightly coupled ecologically. Most often, these oscillations occur between predator and prey (or a pathogen and its host), as demonstrated by the famous case of the Canadian lynx and snowshoe hare, documented in the trapping records of the Hudson's Bay Company. This makes sense—as the predator depletes th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Human Reproduction
سال: 2015
ISSN: 0268-1161,1460-2350
DOI: 10.1093/humrep/dev289